「部位特異性」に関連した英語例文の一覧と使い方

ＴＧ１ファージの特異的部位（ａｔｔＰ_TG1）に対応する宿主菌Ｓ．ａｖｅｒｍｉｔｉｌｉｓの特異的部位（ａｔｔＢ_TG1）と相同性が高い塩基配列をゲノム上に有する放線菌およびプロテオバクテリアを用い、ＴＧ１インテグラーゼを利用した部位特異的遺伝子組換法および該部位特異的遺伝子組換法による微生物ゲノム改変法を提供する。例文帳に追加

There are provided: a site-specific genetic recombination method using actinomyces and proteobacteria having, on a genome, a base sequence having high homology to a specific site (attB_TG1) of host strain S. avermitilis corresponding to a specific site (attP_TG1) of TG1 phage and utilizing TG1 integrase; and a method for modifying a microbial genome by the site-specific genetic recombination method. - 特許庁

生体関連物質の非特異吸着防止剤は、生分解性部位を有する主鎖と、低非特異吸着性部位を有する側鎖とを有するコーム型ポリマーを含有する。例文帳に追加

A nonspecific adsorption preventing agent of biological materials contains the comb-shaped polymer having a main chain with a biodegradable site and a side chain with a low nonspecifically adsorbing site. - 特許庁

小腸内部位特異的薬物デリバリーのための腸溶性コーティング基剤で被覆した腸溶性製剤例文帳に追加

ENTERIC-COATED PREPARATION COVERED WITH ENTERIC COATING MATERIAL FOR SITE-SPECIFIC DELIVERY OF DRUG TO SITE WITHIN SMALL INTESTINE - 特許庁

小腸内部位特異的に薬物をデリバリーすることの出来る腸溶性コーティング基剤を用いて、腸溶性製剤を提供する。例文帳に追加

To provide an enteric-coated preparation prepared by using an enteric coating material capable of delivering a drug to a site in the small intestine in a site-specific manner. - 特許庁

例文

このような更なる特性は、ヌクレアーゼ耐性、特異的細胞または細胞内の特異的部位に配置する特異細胞リセプターをターゲットとし、そして該構築物と対象とする細胞との間の相互作用を、所望なればこのような相互作用を減少するのみならず増大させることを含む。例文帳に追加

Such additional characteristics include nuclease resistance, targeting specific cells or specific cell receptors localizing to specific sites within cells and augmenting interactions between the compositions and target cells of interest as well as decreasing such interactions when desired. - 特許庁

例文

インビボで患者に投与された際に標的部位に対して高特異性を有するビオチン化合物を特徴とする。例文帳に追加

The present invention provides biotin compounds that have a high specificity for target sites when administered to a subject in vivo. - 特許庁

外来性遺伝子のゲノム上部位特異的挿入により作製されたトランスジェニック又はキメラ動物例文帳に追加

TRANSGENIC OR CHIMERIC ANIMAL OBTAINED BY SITE-SPECIFIC INSERTION OF FOREIGN GENE INTO GENOME - 特許庁

フラップエンドヌクレアーゼの基質結合部位に変異を導入し、基質特異性が変化した変異体を得る。例文帳に追加

A mutation is introduced into the substrate-binding site of flap endonuclease to prepare a mutant with modified substrate specificity. - 特許庁

有害物質のみを保持する特異性を有した抗原認識部位17は、保持物質26の一端部に位置する。例文帳に追加

An antigen-recognizing site 17 having specificity for holding only the toxic substance is positioned at one terminal part of a holding material 26. - 特許庁

被検出物質と特異的に化学結合する部位を有するプローブ分子からなる導電性高分子層１を備えた。例文帳に追加

This chemical biosensor includes a conductive polymer layer 1 constituted by probe molecules having a part specifically and chemically bonding to a substance to be detected. - 特許庁

外来性ＤＮＡ断片の、植物ゲノム中のあらかじめ選ばれた挿入部位への特異的導入のための方法を提供する。例文帳に追加

To provide a method for specific introduction of a foreign DNA fragment into a preselected insertion site of a genome of a plant. - 特許庁

抗体が有する２以上の特異的結合部位の活性を維持可能な抗体の修飾方法の提供。例文帳に追加

To provide a method for modifying an antibody while keeping the activity of two or more specific binding sites of the antibody. - 特許庁

この配列を欠失させたり、または部位特異的変異導入法によりこの配列に変異を導入すると、転写活性が著しく低下した。例文帳に追加

The transcription activity is considerably lowered by deleting the sequence or transducing a variation from/into the sequence by a site-specific mutagenesis. - 特許庁

機能性非天然型タンパク質の製造法、及び当該タンパク質の部位特異的修飾・固定化法例文帳に追加

METHOD FOR PRODUCING FUNCTIONAL NON-NATURAL PROTEIN, AND METHOD FOR SITE-SPECIFIC MODIFICATION/IMMOBILIZATION OF THE PROTEIN - 特許庁

喘息及び炎症性腸疾患を含む特異的及び非特異的炎症の治療において有用な、ならびに炎症の診断及び炎症部位の位置決めにおいて有用なヒト化組換え抗ＶＬＡ４抗体分子を提供すること。例文帳に追加

To provide humanized recombinant anti-VLA-4 antibody molecules useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease and also useful for diagnosing inflammation and positioning sites of inflammation. - 特許庁

光照射によって、照射部位特異的に、照射直後に速やかに細胞接着分子を介した特異的な細胞接着性を持つ基板を作成する。例文帳に追加

To obtain a cell culture substrate that has a quick specific cellular adhesiveness via cell adhesion molecules, immediately after irradiation that is specific to an irradiated part by light irradiation. - 特許庁

次に、細菌中に前以って導入した別個の遺伝子が配列特異性ヌクレアーゼを発現して上記線状ＤＮＡ構築物上に位置する特異な認識部位で細菌ゲノムを切断する。例文帳に追加

Next, a separate gene previously introduced into the bacterium expresses a sequence-specific nuclease to cut the bacterial genome at a unique recognition site located on the linear DNA construct. - 特許庁

生体内に投与した後、目的部位に特異的且つ効率的に集積し、各種癌および疾病を含む部位を特異的且つ安全に検出・診断することができるＭＲＩ造影剤として又は磁場療法に利用することができる安定な有機磁性ナノ複合体を提供すること。例文帳に追加

To provide a stable organic magnetic nanocomplex utilizable as an MRI contrast agent specifically and safely detecting and diagnosing a site including various cancers and diseases by specifically and efficiently accumulating in a target site after being administered to a living body, or utilizable for a magnetic field therapy. - 特許庁

二重特異性オリゴヌクレオチドを使用した鋳型依存性（ｔｅｍｐｌａｔｅ−ｄｅｐｅｎｄｅｎｔ）伸長反応（ｅｘｔｅｎｓｉｏｎｒｅａｃｔｉｏｎ）による多様な方法、及び３つの異なるＴ_ｍ部位を含む二重特異性オリゴヌクレオチド。例文帳に追加

The present invention relates to various processes by a template-dependent extension reaction using a dual specificity oligonucleotide and a dual specificity oligonucleotide composed of three different T_m portions therefor. - 特許庁

大腸菌内での発現に最適化されたネイティブ配列部位特異的突然変異誘発、ランダム突然変異誘発または「部位飽和」突然変異誘発によって得られた、セファロスポリンＣアシラーゼ活性を有する酵素。例文帳に追加

Disclosed is an enzyme having a cephalosporin C acylase activity obtained by native sequence site-specific mutagenesis, random mutagenesis or site-saturated mutagenesis that are optimized to express in Escherichia coli. - 特許庁

次いで、それらのスペクトルをクロスした全アミノ酸周波数スペクトルからその蛋白質の活性部位由来の特異的振動数値を選択し、特異的振動数値の近似値を検索することにより任意の蛋白質の生物・機能活性を予測する。例文帳に追加

Subsequently, a specific frequency value derived from the active site of the protein is selected from a total amino acid frequency spectrum obtained by crossing these spectra, an approximate value of the specific frequency is retrieved, and consequently, a biological/functional activity of the optional protein is predicted. - 特許庁

その結果、動脈硬化切片の免疫染色ができる酸化LDL/β_2GPI複合体抗体の中でも、特定のエピトープに特異性を有する酸化LDL/β_2GPI複合体抗体の標識体が、粥状動脈硬化の存在部位の特異的なイメージングに有効であることが明らかとなった。例文帳に追加

Consequently, it has been found that an oxidized LDL/β_2GPI complex antibody labeled product having specificity to a specific epitope, among the oxidized LDL/β_2GPI complex antibodies capable of imminostaining arteriosclerotic sections is effective for the specific imaging of the existing site of atherosclerosis. - 特許庁

MNタンパク質の炭酸脱水酵素ドメインの酵素活性中心内の部位であって特定のアミノ酸配列を含む部位に結合しかつ該部位に特異的に結合するため炭酸脱水酵素阻害剤によって溶出される分子を同定することを含む方法。例文帳に追加

The method includes identifying a molecule eluted by a carbonic anhydrase inhibitor since the molecules specifically bind to a site in the center of an enzyme activity of a carbonate dehydratase domain of a MN protein or a portion containing a specific amino acid sequence. - 特許庁

GUS発現量を指標として、各プロモーターによる発現部位、種子成熟過程での発現、さらに種子での発現強度を検討したところ、種子の特定部位に特異的発現活性を有し、恒常的プロモーターや既知の種子特異的プロモーターと比較して高い活性をもつプロモーターを見出した。例文帳に追加

A promoter having specific expression activity at the specific site of the seed and higher activity than those of regular promoters and known seed-specific promoters has been found by examining expression sites by each promoter, expression during the maturation process of the seeds and expression intensity in the seeds, using GUS expression amount as an index. - 特許庁

By using the GUS expression amounts as an index, the expressed positions, the expression during the maturation period and further the expression strength in the seeds by each of the promoters are examined and the promoters having specific expression activities at specific positions of the seeds and higher activities than those of constant promoters or known seed specific promoters are found out. - 特許庁

The expressed positions, the expression during the maturation period and further the expression intensity in the seeds by each of the promoters are examined by use of the GUS expression amounts as an index and the promoters having specific expression activity at specific positions of the seeds and having higher activity than constant promoters or well-known seed-specific promoters are found out. - 特許庁

A promoter having a specific expression activity at the specific site of the seeds and higher activity than those of promoters and known seed-specific promoters has been found by examining expression sites by each promoter, expression during the maturation process of the seeds and expression strength in the seeds using GUS expression amount as an index. - 特許庁

生理活性の低下を抑えつつ非天然アミノ酸を高効率で部位特異的に組込むのが容易な非天然蛋白質の製造方法、その製造方法により製造された非天然蛋白質、及び生理活性の低下を抑えつつ部位特異的に非天然蛋白質を固定化するのが容易な非天然蛋白質の固定化方法を提供する。例文帳に追加

To provide a method for producing a non-natural protein, easily incorporating a non-natural amino acid as position specifically in a high efficiency while suppressing the reduction of physiological activity, a non-natural protein produced by the method, and a method for immobilizing the non-natural protein easily immobilizing the same as position specifically while suppressing the reduction of physiological activity. - 特許庁

An expression site by each promoter, an expression in a seed maturation process and an expression strength in a seed are examined by using an expression amount of GUS as an index and thereby a promoter that has specific expression activity at a specific site of seed and higher activity than those of a constant promoter and a known seed-specific promoter has been found. - 特許庁

アミロイドβタンパク質に対する高い結合特異性、高い血液脳関門の透過性、脳内老人斑以外の部位からの速やかな消失性を併せ持つ化合物を提供する。例文帳に追加

To provide a compound that exhibits high bonding specificity to an amyloid β protein and high permeability through blood brain barriers as well as rapid disappearance from a region other than intracerebral senile plaque. - 特許庁

アミロイドβ蛋白に対する高い結合特異性、高い血液脳関門の透過性、脳内老人斑以外の部位からの速やかな消失性を併せ持つ化合物を提供する。例文帳に追加

To provide a compound simultaneously having high binding specificity to amyloid β-protein, high capability of permeating through the blood-brain barrier and a high rate of disappearance from regions other than intracerebral senile plaque. - 特許庁

タンパク質補充療法を活性部位特異的シャペロン（ＡＳＳＣ）と組み合わせることによって、投与されるタンパク質の安定性及び有効性を高め、タンパク質補充療法を改善する方法を提供する。例文帳に追加

To provide a method of improving protein replacement therapy by combining protein replacement therapy with active site-specific chaperones (ASSC) to increase the stability and efficiency of protein being administered. - 特許庁

表面の少なくとも一部に金属を含む構造体と、構造体に対して親和性を有する金属結合部位及び細胞表面抗原に対して親和性を有する細胞表面抗原結合部位を有する多重特異性分子とで温熱素子を構成する。例文帳に追加

The thermoelement comprises a structure containing a metal on at least a part of a surface, a metal bond part having affinity for the structure and multiple specific molecules having a cell surface antigen bond part with affinity for a cell surface antigen. - 特許庁

標的物質に対する結合部位を有する第１のドメインと、非特異吸着抑制剤に対する結合部位を有する第２のドメインを組み合わせて結合性タンパク分子を形成し、基体表面に配置した非特異吸着抑制剤に対して第２のドメインを介してこれを結合することで、標的物質捕捉用の基体−タンパク質複合体からなる素子を得る。例文帳に追加

An element comprising the substrate-protein complex for capturing the target substance is obtained by combining a first domain which has a binding site to the target substance and a second domain which has a binding site to an inhibitor of non-specific adsorption, so as to form a binding protein molecule, and then binding the molecule to the inhibitor of non-specific adsorption arranged on a surface of a substrate through the second domain. - 特許庁

淋菌の検出及びニューキノロン剤感受性評価を行う方法であって、以下のステップを含む： (1) 淋菌gyrA遺伝子において特定の多型部位をコードする領域を含むターゲットDNAを特異的に増幅させるステップ； (2) 前記ターゲットDNAと、該ターゲットDNAの前記多型部位を含む部分に特異的にハイブリダイズ可能な核酸プローブとの融解温度を解析するステップ。例文帳に追加

This method for performing the detection of the gonococcus and new quinolone medicine sensitivity evaluation of the gonococcus includes the following steps: (1) a step for specifically amplifying a target DNA containing a region encoding a specific polymorphic site in gonococcus gyr A gene; and (2) a step for analyzing the fusion temperature of the target DNA with a nucleic acid probe which can specifically hybridize with a portion containing the polymorphic site. - 特許庁